SGCA anticorps (AA 24-387)

N° du produit ABIN3043432

Cet anticorps Lapin Polyclonal détecte spécifiquement SGCA dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SGCA anticorps (AA 24-387) (ABIN3043432)

Antigène: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SGCA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SGCA anticorps

Épitope: AA 24-387

Fonction: Anti-alpha Sarcoglycan/SGCA Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-alpha Sarcoglycan/SGCA Antibody Picoband® (ABIN3043432). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. "Entrez Gene: SGCA sarcoglycan, alpha (50 kDa dystrophin-associated glycoprotein)". 2. McNally EM, Yoshida M, Mizuno Y, Ozawa E, Kunkel LM (Nov 1994). "Human adhalin is alternatively spliced and the gene is located on chromosome 17q21". Proc Natl Acad Sci U S A 91 (21): 9690-4.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur SGCA

Antigène: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Autre désignation: SGCA

Sujet:

Synonyms: Alpha-sarcoglycan,Alpha-SG,50 kDa dystrophin-associated glycoprotein,50DAG,Adhalin,Dystroglycan-2,SGCA,ADL, DAG2,

Tissue Specificity: Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung. Also detected in liver and kidney. Not expressed in brain.

Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Sequence Similarities: Belongs to the sarcoglycan alpha/epsilon family.

Poids moléculaire: 43 kDa

ID gène: 6442

UniProt: Q16586