SIRT6 anticorps (AA 14-180)
Aperçu rapide pour SIRT6 anticorps (AA 14-180) (ABIN3043435)
Antigène
Voir toutes SIRT6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 14-180
-
Fonction
- Anti-SIRT6 Antibody
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins.
-
Attributs du produit
- Anti-SIRT6 Antibody (ABIN3043435). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human SIRT6 recombinant protein (Position: D14-E180). Human SIRT6 shares 95% amino acid (aa) sequence identity with mouse SIRT6.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human
-
Commentaires
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- SIRT6 (Sirtuin 6 (SIRT6))
-
Autre désignation
- SIRT6
-
Sujet
-
Synonyms: NAD-dependent protein deacetylase sirtuin-6,3.5.1.-,Regulatory protein SIR2 homolog 6,SIR2-like protein 6,SIRT6,SIR2L6,
Background: SIRT6 is also known as SIR2L6. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. Alternative splicing results in multiple transcript variants.
Sequence Similarities: Belongs to the sirtuin family. Class IV subfamily.
-
Poids moléculaire
- 39-42 kDa
-
ID gène
- 51548
-
UniProt
- Q8N6T7
Antigène
-