POT1 anticorps (N-Term)

N° du produit ABIN3043444

Détail du produit anti-POT1 anticorps

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Épitope: AA 195-234, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Protection of telomeres protein 1(POT1) detection. Tested with WB in Human.

Séquence: RVLIQDLVLE GDLSHIHRLQ NLTIDILVYD NHVHVARSLK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protection of telomeres protein 1(POT1) detection. Tested with WB in Human.
Gene Name: protection of telomeres 1
Protein Name: Protection of telomeres protein 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human POT1 (195-234aa RVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLK), different from the related mouse sequence by eleven amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: POT1 (POT1 Produits)

Synonymes: anticorps HPOT1, anticorps POT1, anticorps DKFZp469P1825, anticorps pot1, anticorps 1500031H18Rik, anticorps AI851169, anticorps Pot1, anticorps Pot1a, anticorps protection of telomeres 1, anticorps protection of telomeres 1 L homeolog, anticorps protection of telomeres 1A, anticorps POT1, anticorps pot1.L, anticorps Pot1a, anticorps Pot1

Sujet: Protection of telomeres protein 1 is a protein that in humans is encoded by the POT1 gene. This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Synonyms: DKFZP586D211 antibody|hPot 1 antibody|hPot1 antibody|POT 1 antibody|POT1 antibody|POT1 like telomere end-binding protein antibody|POT1 protection of telomeres 1 homolog antibody|POT1-like telomere end-binding protein antibody|POTE1_HUMAN antibody|Protection of telomeres 1 antibody|Protection of telomeres 1 homolog (S. pombe) antibody|Protection of telomeres protein 1 antibody

ID gène: 25913

Pathways: Cycle Cellulaire, Telomere Maintenance