MUC5AC anticorps (AA 4848-5030)
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- Antigène Voir toutes MUC5AC Anticorps
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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Épitope
- AA 4848-5030
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MUC5AC est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Mucin-5AC(MUC5AC) detection. Tested with WB, IHC-P in Human.
Gene Name: mucin 5AC, oligomeric mucus/gel-forming
Protein Name: Mucin-5AC - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human Mucin 5AC recombinant protein (Position: D4848-H5030).
- Isotype
- IgG
- Top Product
- Discover our top product MUC5AC Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Mucin 5AC is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2." dans: Molecular and cellular biochemistry, Vol. 377, Issue 1-2, pp. 75-85, (2013) (PubMed).
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Neutrophil elastase induces MUC5AC secretion via protease-activated receptor 2." dans: Molecular and cellular biochemistry, Vol. 377, Issue 1-2, pp. 75-85, (2013) (PubMed).
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- Antigène
- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
- Autre désignation
- MUC5AC (MUC5AC Produits)
- Synonymes
- anticorps MUC5, anticorps TBM, anticorps leB, anticorps 2210005L13Rik, anticorps MGM, anticorps mucin 5AC, oligomeric mucus/gel-forming, anticorps putative gastric mucin, anticorps mucin 5, subtypes A and C, tracheobronchial/gastric, anticorps mucin 2, oligomeric mucus/gel-forming, anticorps MUC5AC, anticorps Smp_144070, anticorps Muc5ac, anticorps MUC2
- Sujet
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Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. MUC5AC is also a direct and critical mediator of resistance during intestinal nematode infection.
Synonyms: Apomucin antibody|Gastric mucin antibody|LeB antibody|Lewis B blood group antigen antibody|Major Airway Glycoprotein antibody|MUC 5 antibody|MUC5 antibody|MUC5AC antibody|Mucin 5 subtype AC tracheobronchial antibody|Mucin 5 Subtypes A And C antibody|Mucin 5 subtypes A and C tracheobronchial/gastric antibody|Mucin 5AC antibody|Mucin 5AC oligomeric mucus/gel forming antibody|Mucin 5AC, oligomeric mucus/gel forming pseudogene antibody|TBM antibody|Tracheobronchial Mucin antibody - ID gène
- 4586
- UniProt
- P98088
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