DDB2 anticorps (AA 1-115)

N° du produit ABIN3043488

Détail du produit anti-DDB2 anticorps

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Épitope: AA 1-115

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDB2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for DNA damage-binding protein 2(DDB2) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for DNA damage-binding protein 2(DDB2) detection. Tested with WB in Human.
Gene Name: damage-specific DNA binding protein 2
Protein Name: DNA damage-binding protein 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DDB2 recombinant protein (Position: M1-T115). Human DDB2 shares 58.3% amino acid (aa) sequence identity with mouse DDB2.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur DDB2

Antigène: DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

Autre désignation: DDB2 (DDB2 Produits)

Synonymes: anticorps 2610043A19Rik, anticorps si:dkey-45f10.3, anticorps DDBB, anticorps UV-DDB2, anticorps damage specific DNA binding protein 2, anticorps damage-specific DNA binding protein 2, anticorps DDB2, anticorps ddb2, anticorps Ddb2

Sujet: DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: damage-specific DNA binding protein 2 antibody|Damage-specific DNA-binding protein 2 antibody|DDB p48 subunit antibody|Ddb2 antibody| DDB2_HUMAN antibody|DDBb antibody|DNA damage-binding protein 2 antibody|UV-damaged DNA-binding protein 2 antibody|UV-DDB 2 antibody| Xeroderma pigmentosum group E protei antibody

ID gène: 1643

UniProt: Q92466

Pathways: Réparation de l'ADN