TREX1 anticorps (Middle Region)

N° du produit ABIN3043537

Cet anticorps Lapin Polyclonal détecte spécifiquement TREX1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour TREX1 anticorps (Middle Region) (ABIN3043537)

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TREX1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TREX1 anticorps

Épitope: AA 156-185, Middle Region

Fonction: Anti-TREX1 Antibody Picoband®

Séquence: DDNLANLLLA FLRRQPQPWC LVAHNGDRYD

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TREX1 Antibody Picoband® (ABIN3043537). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TREX1, different from the related mouse sequence by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: TREX1 three prime repair exonuclease 1". 2. Mazur DJ, Perrino FW (Aug 1999). "Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases". J Biol Chem 274 (28): 19655-60.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur TREX1

Antigène: TREX1 (three Prime Repair Exonuclease 1 (TREX1))

Autre désignation: TREX1

Sujet:

Synonyms: Three-prime repair exonuclease 1,3.1.11.2,3'-5' exonuclease TREX1,DNase III,TREX1,

Tissue Specificity: Detected in thymus, spleen, liver, brain, heart, small intestine and colon. .

Background: Three prime repair exonuclease 1 is an enzyme that in humans is encoded by the TREX1 gene. This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. It is also a component of the SET complex, and acts to rapidly degrade 3' ends of nicked DNA during granzyme A-mediated cell death. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 33 kDa

ID gène: 11277

Pathways: Apoptose