Caveolin 2 anticorps (AA 1-162)
Aperçu rapide pour Caveolin 2 anticorps (AA 1-162) (ABIN3043749)
Antigène
Voir toutes Caveolin 2 (CAV2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-162
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Fonction
- Anti-Caveolin-2/CAV2 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human Caveolin-2 shares 90%,89% amino acid (aa) sequences identity with mouse,rat Caveolin-2,respectively.
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Attributs du produit
- Anti-Caveolin-2/CAV2 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Caveolin-2 recombinant protein (Position: M1-D162). Human Caveolin-2 shares 90% and 89% amino acid (aa) sequences identity with mouse and rat Caveolin-2, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat Immunofluorescence, 2 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." dans: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
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- Caveolin 2 (CAV2)
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Autre désignation
- CAV2
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Sujet
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Background: Caveolin-2 is a protein that in humans is encoded by the CAV2 gene. It is mapped to 7q31.1-q31.2. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. Caveolin-2 is a protein related to caveolin-1 which is derived caveolin-enriched membranes. CAV2 and CAV1 are similar in most respects and they differ in their functional interactions with heterotrimeric G proteins. Both of them are expressed in neuronal cells. Caveolin-2 was upregulated in response to neuronal cell injury.
Gene Full Name: caveolin 2
Sequence Similarities: Belongs to the caveolin family.
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Poids moléculaire
- 21 kDa
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ID gène
- 858
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UniProt
- P51636
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development
Antigène
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