ATP2A1/SERCA1 anticorps (N-Term)

N° du produit ABIN3043792

Cet anticorps Lapin Polyclonal détecte spécifiquement ATP2A1/SERCA1 dans WB, IHC et FACS. Il présente une réactivité avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour ATP2A1/SERCA1 anticorps (N-Term) (ABIN3043792)

Antigène: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2A1/SERCA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-ATP2A1/SERCA1 anticorps

Épitope: AA 1-32, N-Term

Fonction: Anti-SERCA1 ATPase/ATP2A1 Antibody

Séquence: MEAAHAKTTE ECLAYFGVSE TTGLTPDQVK RN

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-SERCA1 ATPase/ATP2A1 Antibody (ABIN3043792). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SERCA1 ATPase, different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur ATP2A1/SERCA1

Antigène: ATP2A1/SERCA1 (ATP2A1) (ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1))

Autre désignation: ATP2A1

Sujet:

Synonyms: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1,SERCA1,SR Ca (2+)-ATPase 1,3.6.3.8,Calcium pump 1,Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform,Endoplasmic reticulum class 1/2 Ca (2+) ATPase,ATP2A1,

Tissue Specificity: Skeletal muscle, fast twitch muscle (type II) fibers.

Background: SERCA1, also called ATP2A1, is an enzyme that in humans is encoded by the ATP2A1 gene. This gene encodes one of the SERCA Ca (2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. The SERCA1 gene is mapped to 16p11.2. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. It has been determined that the human SERCA1 gene is 26 kb long and contains 23 exons, of which can be alternatively spliced. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise.

Poids moléculaire: 110 kDa

ID gène: 487

UniProt: O14983

Pathways: Ribonucleoside Biosynthetic Process