Glutathione Peroxidase 1 anticorps (Middle Region)

N° du produit ABIN3043834

Détail du produit anti-Glutathione Peroxidase 1 anticorps

Antigène: Glutathione Peroxidase 1 (GPX1)

Épitope: AA 116-146, Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glutathione Peroxidase 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Glutathione peroxidase 1(GPX1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: EVNGAGAHPL FAFLREALPA PSDDATALMT D

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Glutathione peroxidase 1(GPX1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: glutathione peroxidase 1
Protein Name: Glutathione peroxidase 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human GPX1(116-146aa EVNGAGAHPLFAFLREALPAPSDDATALMTD), different from the related mouse sequence by six amino acids and from the related rat sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for GPX1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Glutathione Peroxidase 1

Antigène: Glutathione Peroxidase 1 (GPX1)

Autre désignation: GPX1 (GPX1 Produits)

Synonymes: anticorps Gpx, anticorps ATGPX1, anticorps F13D4.40, anticorps F13D4_40, anticorps GLUTATHIONE PEROXIDASE 1, anticorps glutathione peroxidase 1, anticorps gshpx1, anticorps AI195024, anticorps AL033363, anticorps CGPx, anticorps GPx-1, anticorps GSHPx-1, anticorps GPX1, anticorps gpx1, anticorps cb690, anticorps zgc:92737, anticorps zgc:103683, anticorps GPXD, anticorps GSHPX1, anticorps GSHPx, anticorps wu:fd42f12, anticorps wu:fj22d06, anticorps zgc:101700, anticorps glutathione peroxidase Gpx1, anticorps glutathione peroxidase, anticorps glutathione peroxidase 1, anticorps glutathione peroxidase 1a, anticorps glutathione peroxidase family protein, anticorps proliferating cell nuclear antigen, anticorps glutathione peroxidase 1b, anticorps glutathione peroxidase 1 S homeolog, anticorps gpx1, anticorps GPX1, anticorps gpx, anticorps Gpx, anticorps Gpx1, anticorps gpx1a, anticorps POPTR_0003s12620g, anticorps Pcna, anticorps LBL_RS00590, anticorps btuE-1, anticorps GPX2, anticorps gpx1b, anticorps gpx1.S

Sujet: Glutathione peroxidase 1, also known as, GPX-1 is an enzyme that in humans is encoded by the GPX1 gene. It is mapped to 3p21.31. This gene encodes a member of the glutathione peroxidase family, consisting of eight known glutathione peroxidases (Gpx1-8) in humans. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. It has been reported that the protein encoded by this gene protects from CD95-induced apoptosis in cultured breast cancer cells and inhibits 5-lipoxygenase in blood cells, and its overexpression delays endothelial cell growth and increases resistance to toxic challenges. GPX1 is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA.

Synonyms: AL033363 antibody|Cellular glutathione peroxidase antibody|Glutathione peroxidase 1 antibody|Glutathione peroxidase antibody|GPx 1 antibody|GPx-1 antibody|GPX1 antibody|GPX1_HUMAN antibody|GPXD antibody|GSHPx-1 antibody|GSHPX1 antibody|MGC14399 antibody|MGC88245 antibody

ID gène: 2876

UniProt: P07203

Pathways: Thyroid Hormone Synthesis, Sensory Perception of Sound, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome