Transglutaminase 2 anticorps (N-Term)

N° du produit ABIN3043946

Détail du produit anti-Transglutaminase 2 anticorps

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Épitope: AA 7-34, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Transglutaminase 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for Protein-glutamine gamma-glutamyltransferase 2(TGM2) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.

Séquence: LERCDLELET NGRDHHTADL CREKLVVR

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protein-glutamine gamma-glutamyltransferase 2(TGM2) detection. Tested with WB, IHC-P, IHC-F in Human,Mouse,Rat.
Gene Name: transglutaminase 2
Protein Name: Protein-glutamine gamma-glutamyltransferase 2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human TGM2 (7-34aa LERCDLELETNGRDHHTADLCREKLVVR), different from the related mouse sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for TGM2 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Transglutaminase 2

Antigène: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Autre désignation: TGM2 (TGM2 Produits)

Synonymes: anticorps G-ALPHA-h, anticorps GNAH, anticorps TG2, anticorps TGC, anticorps tgm2, anticorps zgc:101081, anticorps TgaseII, anticorps TGM2, anticorps fc12b04, anticorps wu:fc12b04, anticorps zgc:136700, anticorps TGL2, anticorps G[a]h, anticorps TGase2, anticorps tTG, anticorps tTGas, anticorps transglutaminase 2, anticorps transglutaminase 2, C polypeptide A, anticorps transglutaminase 2b, anticorps transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase), anticorps transglutaminase 2, C polypeptide, anticorps TGM2, anticorps tgm2a, anticorps Tgm2, anticorps tgm2b

Sujet: Tissue transglutaminase, also called TGC, is a 78- kDa, calcium dependent enzyme of the protein-glutamine gamma-glutamyltransferases family. By fluorescence in situ hybridization (FISH), this gene is mapped in 20q11.23. Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease.

Synonyms: ALPHA SUBUNIT antibody|C polypeptide antibody|EC 2.3.2.13 antibody|G alpha h antibody|G protein alpha subunit Gh class antibody|G[a]h antibody|Gh CLASS G ALPHA h antibody|GNAH antibody|GNAH G PROTEIN antibody|Guanine nucleotide binding protein H polypeptide antibody| H POLYPEPTIDE antibody|Protein glutamine gamma glutamyltransferase 2 antibody| Protein glutamine gamma glutamyltransferase antibody|Protein-glutamine gamma-glutamyltransferase 2 antibody|TG 2 antibody|TG(C) antibody|TG2 antibody|TGase C antibody| TGase H antibody| TGase-2 antibody|TgaseII antibody|TGC antibody|TGC GUANINE NUCLEOTIDE BINDING PROTEIN antibody|TGM 2 antibody|TGM2 antibody|TGM2_HUMAN antibody|Tissue transglutaminase antibody| Tissue type transglutaminase antibody|Transglutaminase 2 antibody|Transglutaminase 2 C polypeptide antibody|Transglutaminase C antibody| Transglutaminase H antibody| Transglutaminase-2 antibody|tTG antibody|tTGas antibody

ID gène: 7052

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling