IGF2R anticorps (C-Term)

N° du produit ABIN3044000

Il existe 1 publication pour ce produit. L’anticorps anti-IGF2R Polyclonal Lapin est utilisé pour la détection de IGF2R dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et FACS.

Aperçu rapide pour IGF2R anticorps (C-Term) (ABIN3044000)

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGF2R est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-IGF2R anticorps

Épitope: C-Term

Fonction: Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody

Séquence: TKLVSFHDDS DEDLLHI

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by one amino acid.

Attributs du produit: Anti-Mannose 6 Phosphate Receptor (Cation independent)/IGF2R Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Mannose 6 Phosphate Receptor(Cation independent), different from the related rat and mouse sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IGF2R (ABIN3044000)

Liang, Hao, Zhang, Wu, Wang: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." dans: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).

Détails sur IGF2R

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Autre désignation: IGF2R

Sujet:

Background: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Gene Full Name: insulin like growth factor 2 receptor

Sequence Similarities: Belongs to the MRL1/IGF2R family.

Poids moléculaire: 274 kDa

ID gène: 3482

UniProt: P11717