Tec Protein Tyrosine Kinase (TEC) (C-Term) anticorps

N° du produit ABIN3044046

Cet anticorps anti-Tec Protein Tyrosine Kinase Polyclonal Lapin (ABIN3044046) détecte spécifiquement Tec Protein Tyrosine Kinase dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour Tec Protein Tyrosine Kinase (TEC) (C-Term) anticorps (ABIN3044046)

Antigène: Tec Protein Tyrosine Kinase (TEC)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit

Épitope: C-Term

Fonction: Anti-Tyrosine-protein kinase Tec Tec Antibody

Séquence: FEDLLRTIDE LVECEETFGR

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence,and different from the related mouse sequence by one amino acid.

Attributs du produit: Anti-Tyrosine-protein kinase Tec Tec Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Tec, identical to the related rat sequence, and different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, RatWestern blot, 0.1-0.5 μg/mL, Human, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Thimerosal, 0.01 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Tec Protein Tyrosine Kinase (TEC)

Autre désignation: TEC

Sujet:

Background: TEC (TEC Protein Tyrosine Kinase), is an enzyme that in humans is encoded by the TEC gene. The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. By fluorescence in situ hybridization, Sato et al. (1994) mapped the gene to 4p12, the same location reported for TXK. Mouse Tec is a non-receptor type protein-tyrosine kinase that is highly expressed in many hematopoietic cell lines. Hantschel et al. (2007) identified TEC kinase and BTK kinase as major binders of the tyrosine kinase inhibitor dasatinib, which is used for treatment of BCR/ABL-positive CML.

Gene Full Name: tec protein tyrosine kinase

Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.

Poids moléculaire: 58-60 kDa

ID gène: 7006

UniProt: P42680

Pathways: Fc-epsilon Receptor Signaling Pathway