ITGA3 anticorps (N-Term)

N° du produit ABIN3044222

L’anticorps anti-ITGA3 Polyclonal Lapin est utilisé pour la détection de ITGA3 dans des échantillons de Humain et Rat. Il a été validé pour WB, FACS, IHC, IF et ICC.

Aperçu rapide pour ITGA3 anticorps (N-Term) (ABIN3044222)

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-ITGA3 anticorps

Épitope: AA 51-67, N-Term

Fonction: Anti-Integrin alpha 3/ITGA3 Antibody

Séquence: LFGYSVALHR QTERQQR

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Integrin alpha 3/ITGA3 Antibody (ABIN3044222). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: ITGA3

Sujet:

Synonyms: Integrin alpha-3,CD49 antigen-like family member C,FRP-2,Galactoprotein B3,GAPB3,VLA-3 subunit alpha,CD49c,Integrin alpha-3 heavy chain,Integrin alpha-3 light chain,ITGA3,MSK18,

Tissue Specificity: Isoform 1 is widely expressed. Isoform 2 is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform 1 is strongly expressed on vascular smooth muscle cells, isoform 2 is detected only on endothelial vein cells. .

Background: ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Sequence Similarities: Belongs to the integrin alpha chain family.

Poids moléculaire: 155 kDa

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex