ITGA3 anticorps (N-Term)

N° du produit ABIN3044222

Détail du produit anti-ITGA3 anticorps

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Épitope: AA 51-67, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Integrin alpha-3(ITGA3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: LFGYSVALHR QTERQQR

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Integrin alpha-3(ITGA3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Protein Name: Integrin alpha-3

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Integrin alpha 3(51-67aa LFGYSVALHRQTERQQR), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur ITGA3

Antigène: ITGA3 (Integrin, alpha 3 (ITGA3))

Autre désignation: ITGA3 (ITGA3 Produits)

Synonymes: anticorps CD49C, anticorps GAP-B3, anticorps GAPB3, anticorps ILNEB, anticorps MSK18, anticorps VCA-2, anticorps VL3A, anticorps VLA3a, anticorps ITGA3, anticorps AA407068, anticorps integrin subunit alpha 3, anticorps integrin subunit alpha 3 S homeolog, anticorps integrin alpha 3, anticorps ITGA3, anticorps itga3.S, anticorps Itga3

Sujet: ITGA3(INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein that in humans is encoded by the ITGA3 gene. ITGA3 is an integrin alpha subunit which is also a member of the family of cell surface adhesion molecules. ITGA3 is mapped to chromosome 17 and its exact cytogenetic location is 17q21.33. ITGA3 makes up half of the alpha3beta1 integrin duplex that plays a role in neural migration and corticogenesis together with beta-1 subunit. A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers. Expression of human ITGA3 increased the infectivity of virus for Chinese hamster ovary cells. ITGA3 also contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and the 7 N-terminal repeating units characteristic of ITGAs. Recombinant ITGA3 is expressed as a 150-kD protein as the same size as the native protein by the western blot analysis.

Synonyms: AA407068 antibody|Antigen identified by monoclonal antibody J143 antibody|CD49 antigen like family member C antibody|CD49 antigen-like family member C antibody|CD49c antibody|CD49c antigen antibody|FLJ34631 antibody|FLJ34704 antibody|FRP 2 antibody|FRP-2 antibody|FRP2 antibody|galactoprotein B3 antibody|GAP B3 antibody|GAPB3 antibody|Integrin alpha 3 antibody|Integrin alpha-3 light chain antibody|Integrin, alpha 3(antigen CD49C, alpha 3 subunit of VLA-3 receptor) antibody|ITA3_HUMAN antibody|ITGA 3 antibody|ITGA3 antibody|MSK18 antibody|URO1 antibody|VCA 2 antibody|VCA2 antibody|Very late activation protein 3 receptor alpha 3 subunit antibody|Very Late Activation Protein 3 Receptor Alpha 3 Subunit antibody|VL3A antibody|VLA 3 alpha chain antibody|VLA 3 subunit alpha antibody|VLA-3 subunit alpha antibody|VLA3 antibody|VLA3a antibody

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex