TRIB2 anticorps (Middle Region)

N° du produit ABIN3044555

L’anticorps Lapin Polyclonal anti-TRIB2 a été validé pour WB et IHC. Il convient pour détecter TRIB2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TRIB2 anticorps (Middle Region) (ABIN3044555)

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TRIB2 anticorps

Épitope: AA 175-211, Middle Region

Fonction: Anti-TRIB2 Antibody Picoband®

Séquence: DLKLRKFIFK DEERTRVKLE SLEDAYILRG DDDSLSD

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TRIB2 Antibody Picoband® (ABIN3044555). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human TRIB2, identical to the related mouse sequence.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: TRIB2 tribbles homolog 2 (Drosophila)". 2. Hegedus Z, Czibula A, Kiss-Toth E (Aug 2006). "Tribbles: novel regulators of cell function, evolutionary aspects". Cell Mol Life Sci 63 (14): 1632-41. 3. Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS (Nov 2006). "Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia". Cancer Cell 10 (5): 401-11.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur TRIB2

Antigène: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Autre désignation: TRIB2

Sujet:

Synonyms: Tribbles homolog 2,TRB-2,TRIB2 ,TRB2 ,

Tissue Specificity: Highly expressed in peripheral blood leukocytes. .

Background: Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 39 kDa

ID gène: 28951

UniProt: Q92519