HLA-B27 anticorps (FITC)
Aperçu rapide pour HLA-B27 anticorps (FITC) (ABIN304843)
Antigène
Voir toutes HLA-B27 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Recognizes the HLA-B27 alloantigen. Reacts with the peripheral blood lymphocytes of 47/47 individuals conventionally typed as HLA-B27 + and precipitates cell surface molecules of 43 and 12 kD, corresponding to the HLA Class 1 heavy chain and beta 2 microglobulin. Affinity studies by Scatchard analysis showed that this has a higher affinity for HLA-B27 (9.7 x 108 M-1) than for HLA B7 (9.5 x 107 M-1). Subjects Expected Fluorescence Intensity Heterozygous HLA-B27+ Strong Homozygous HLA-B27+ Strong Heterozygous HLA-B7+ Faint Non B27, Non B7 Negative.
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Purification
- Ion exchange chromatography
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Immunogène
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Immune complex precipitated from HLA-B27 positive cell line (Bordin) by anti HLA-antibody and Staphylococcal Protein A.
Type of Immunogen: Cells -
Isotype
- IgG2a
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Indications d'application
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Approved: Flo (1:1)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL of whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide, 0.2 % BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- 4°C, avoid freezing.
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- HLA-B27 (HLA Class I Histocompatibility Antigen, B-27 alpha Chain (HLA-B27))
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Autre désignation
- HLA-B27
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Pathways
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Antigène
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