SH3BP4 anticorps

N° du produit ABIN306590

L’anticorps anti-SH3BP4 Polyclonal Mouton est utilisé pour la détection de SH3BP4 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour SH3BP4 anticorps (ABIN306590)

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3BP4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SH3BP4 anticorps

Fonction: Sheep anti Human Guanalyate Kinase GKWW domain (MAGI)

Réactivité croisée: Humain

Attributs du produit: Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is then followed by 6 PDZ domains.

Purification: Ammonium Sulfate Precipitation

Immunogène: Recombinant protein corresponding to the guanylate kinase-WW domain of MAGI-3.

Isotype: IgG

Information d'application

Indications d'application: Antibody detects MAGI-3 by Western blot at 1-10 μg/mL. Detects a 130 kDa band in cells transfected with full-length MAGI-3 protein. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur SH3BP4

Antigène: SH3BP4 (SH3-Domain Binding Protein 4 (SH3BP4))

Autre désignation: Membrane AssociatedGuanalyate Kinase GKWW domain (MAGI)

Sujet: Sheep anti-Membrane-associated guanylate cyclase of inverted orientation-3, Guanylate Kinase-WW domains

UniProt: Q9H2V6