p107 anticorps

N° du produit ABIN306628

Cet anticorps Souris Monoclonal détecte spécifiquement p107 dans . Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour p107 anticorps (ABIN306628)

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp p107 est non-conjugé

Application: Veuillez nous consulter SVP

Clone: KAB6

Détail du produit anti-p107 anticorps

Isotype: IgG1

Information d'application

Restrictions: For Research Use only

Stockage

Détails sur p107

Antigène: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Autre désignation: p107

Sujet: The immunogen used was a GST fusion protein to the N terminus of p107. p107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors. KAB6 recognizes both the phosphorylated and unphosphorylated forms of p107 at a MW of 107kDa. Synonyms: p107, Retinoblastoma-like protein 1, PRB1, 107 kda retinoblastoma-associated protein.

UniProt: P28749

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases