EPH Receptor B1 anticorps (AA 620-1596)

N° du produit ABIN306670

Cet anticorps Mouton Polyclonal détecte spécifiquement EPH Receptor B1 dans WB, IHC et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour EPH Receptor B1 anticorps (AA 620-1596) (ABIN306670)

Antigène: EPH Receptor B1 (EPHB1)

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-EPH Receptor B1 anticorps

Épitope: AA 620-1596

Réactivité croisée: Rat

Attributs du produit: Eph B1 (ELK receptor) SAM, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6,Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells

Purification: Ammonium Sulfate Precipitation

Immunogène: Sheep were immunized with a recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blot (2-5 μg/mL), immunohistochemistry and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur EPH Receptor B1

Antigène: EPH Receptor B1 (EPHB1)

Autre désignation: ELK rec tyr Kinase (Eph B1 SAM)

Pathways: Signalisation RTK