EPH Receptor B1 anticorps (C-Term)

N° du produit ABIN306671

L’anticorps anti-EPH Receptor B1 Polyclonal Mouton est utilisé pour la détection de EPH Receptor B1 dans des échantillons de Humain. Il a été validé pour IP.

Aperçu rapide pour EPH Receptor B1 anticorps (C-Term) (ABIN306671)

Antigène: EPH Receptor B1 (EPHB1)

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp EPH Receptor B1 est non-conjugé

Application: Immunoprecipitation (IP)

Détail du produit anti-EPH Receptor B1 anticorps

Épitope: AA 586-984, C-Term

Fonction: Sheep anti Human ELK rec tyr Kinase (Eph B1 Cy.)

Réactivité croisée: Humain

Attributs du produit: The immunogen used for the anti-human ephB1 (Elk receptor) Dcytoplasmic(CY) region was a GST fusion protein ephB1 (Elk receptor) CY corresponding to amino acid sequence 586-984 of the C terminal, cytoplasmic region and having a molecular weight of 116 kDa. EphB1, previously known as Elk (eph-like kinase), is a receptor tyrosine kinase of the highly tissue restricted family of eph proteins. EphB1 and other ephB family members are type 1 membrane spanning proteins, comprised of immunoglobulin, fibronectin type III, and cysteine rich subdomains in the ecto domain, and the single uninterrupted cytoplasmic tyrosine kinase domain upstream of a carboxyterminal sterile alpha motif (SAM) domain. EphB family proteins bind ephrins of the B class, ligands that are also transmembrane spanning proteins capable of transmitting signals. EphB1 is expressed predominantly in developing neural structures in embryos, and in vascular epithelium of kidney, and other tissues. Upon binding to alternatively oligomerized ephrin B1, ephB1 signals regulation of cell attachment and cell-cell assembly. Members of this protein family are implicated in neuronal and vascular cell targeting.

Purification: Ammonium Sulfate Precipitation

Immunogène: A GST fusion protein ephB1 (Elk receptor) - CY corresponding to amino acid sequence 586-984 of the C terminus region and having a molecular weight of 116 kDa

Isotype: IgG

Information d'application

Indications d'application: Applications: 1-10 μg/mL for Western Blotting and 10-20 μg/mL for immunoprecipitation.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur EPH Receptor B1

Antigène: EPH Receptor B1 (EPHB1)

Autre désignation: ELK rec tyr Kinase (Eph B1 Cy)

Sujet: Eph B1 (ELK receptor) cytoplasmic, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6

UniProt: P54762

Pathways: Signalisation RTK