CAPN1 anticorps (Agarose Beads)
Aperçu rapide pour CAPN1 anticorps (Agarose Beads) (ABIN306691)
Antigène
Voir toutes CAPN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée
- Humain
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Attributs du produit
- Mouse anti calpain I, II small subunit, p30, agarose conjugate,The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (μM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
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Purification
- Protein A/G Chromatography
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Immunogène
- Hybridoma produced by the fusion of splenocytes from mice immunized with human calpain with mouse myeloma.
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Isotype
- IgG1
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Indications d'application
- Application: Use at 0.5-1 μg/mL for ELISA and western blot, 1-2 μg/mL for immunoprecipitation.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Provided as a concentration of 1 mg/mL in 0.02M sodium phosphate, pH 7.5, 0.15M sodium chloride, 50 % glycerol, 3 mM sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CAPN1 (Calpain 1 (CAPN1))
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Autre désignation
- Calpain I
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UniProt
- P17655
Antigène
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