CAPN1 anticorps
Aperçu rapide pour CAPN1 anticorps (ABIN306692)
Antigène
Voir toutes CAPN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Mouse anti Human Calpain I, II (small subunit)
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Réactivité croisée
- Boeuf (Vache), Humain
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Attributs du produit
- The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (μM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
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Purification
- Protein A/G Chromatography
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Isotype
- IgG1
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Indications d'application
- Use at 0.5-1 μg/mL for ELISA and western blot, 1-2 μg/mL for immunoprecipitation.
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Restrictions
- For Research Use only
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CAPN1 (Calpain 1 (CAPN1))
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Autre désignation
- Calpain I
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Sujet
- Mouse anti calpain I, II small subunit, p30
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UniProt
- P17655
Antigène
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