VSX2 anticorps (Visual System Homeobox 2) (N-Term)

N° du produit ABIN306799

Détail du produit anti-VSX2 anticorps

Antigène:

VSX2

Épitope: N-Term

Reactivité: Souris, Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp VSX2 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG

Information d'application

Indications d'application: Detects Chx10 by Western blot at 0.5 to 1 ug/ml. Detects a 46 kDa band in mouse and rat retinal tissue lysates. Positive Control: Rat or mouse retinal tissue lysate.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/ml

Stock: -20 °C

Détails sur VSX2

Antigène:

VSX2

Autre désignation: chx 10 (NT) (VSX2 Antibody Extrait)

Sujet: Chx10 is a 46kDa homeodomain protein of the paired-like class that is essential for development of the mammalian eye. Mutations in Chx10 cause microphthalmia, a cause of congenital blindness in humans, and the ocular retardation (or) phenotype in mice. In the developing mouse retina Chx10 is expressed in retinal progenitors, while in the mature retina, Chx10 expression becomes restricted to bipolar neurons. Concurrent with these expression patterns, the Chx10-/- (or) retina is thin due to a defect in proliferation of retinal progenitors, and lacks bipolar neurons. Chx10 is also expressed in the developing brainstem, thalamus,and spinal cord.

Pathways: Dopaminergic Neurogenesis