Estrogen Receptor alpha anticorps
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- Antigène Voir toutes Estrogen Receptor alpha (ESR1) Anticorps
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Estrogen Receptor alpha est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Enzyme Immunoassay (EIA)
- Réactivité croisée
- Humain, Souris
- Attributs du produit
- The human estrogen receptor has a molecular weight of 67 kDa and consists of 6 functional domains (domains A-F). Functional mapping of the estrogen receptor has determined a transcriptional promoting activity in the A/B domain. The hormone-binding domain (E domain) is located towards the carboxy terminal, whereas the DNA-binding domain (C domain) is found in the central portion of the molecule. It has been speculated that the presence in breast cancer cells of truncated forms of the estrogen receptor lacking the hormone-binding domain might promote the uncontrolled growth of the tumor.
- Purification
- Saturated ammonium sulphate precipitation.
- Immunogène
- Hybridoma produced by the fusion of splenocytes from mice immunized with purified estrogen receptors from calf uterus and mouse myeloma cells.
- Clone
- AER311
- Isotype
- IgG2a
- Top Product
- Discover our top product ESR1 Anticorps primaire
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- Indications d'application
- Antibody can be used for staining of human and mouse frozen and paraffin tissue sections. Optimal concentration should be evaluated by serial dilutions. Other Applications: Immunoprecipitation, Western Blotting, ELISA.
- Restrictions
- For Research Use only
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- Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Antigène
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Autre désignation
- Estrogen Receptor (ESR1 Produits)
- Synonymes
- anticorps LOC398734, anticorps AA420328, anticorps AU041214, anticorps ER-alpha, anticorps ER[a], anticorps ERa, anticorps ERalpha, anticorps ESR, anticorps Estr, anticorps Estra, anticorps Nr3a1, anticorps NR3A1, anticorps eralpha, anticorps zfER[a], anticorps ER, anticorps ESRA, anticorps ESTRR, anticorps Era, anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps Esr, anticorps RNESTROR, anticorps ERALPHA, anticorps er, anticorps esr, anticorps nr3a1, anticorps XER, anticorps era, anticorps esra, anticorps ERbeta, anticorps xesr-1, anticorps xlERalpha1, anticorps xlERalpha2, anticorps ESR1, anticorps estrogen receptor 1 L homeolog, anticorps estrogen receptor 1 (alpha), anticorps estrogen receptor 1, anticorps A kinase (PRKA) anchor protein 12b, anticorps esr1.L, anticorps Esr1, anticorps ESR1, anticorps esr1, anticorps akap12b
- UniProt
- P03372
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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