KCNA1 anticorps

N° du produit ABIN306869

L’anticorps anti-KCNA1 Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de KCNA1 dans des échantillons provenant de Rat. }

Aperçu rapide pour KCNA1 anticorps (ABIN306869)

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNA1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KCNA1 anticorps

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Voltage-Gated Potassium Channel, Kv1.1 isoform,K+ channels from the Kv1 subfamily contain four alpha-subunits and the combinations (from Kv1.1-1.6) determine susceptibility to dendrotoxin (DTX) homologue. Kv1.1, a Shaker-like voltage-gated potassium channel, is strongly expressed in a variety of neurons in adult rodents, in which it appears to be involved in regulating neuronal excitability. Here we show that Kv1.1 is also expressed during embryonic development in the mouse, exhibiting two transient peaks of expression around embryonic day 9.5 (E9.5) and E14.5. Potassium channels play a critical role in limiting neuronal excitability. Mutations in certain voltage-gated potassium channels have been associated with hyperexcitable phenotypes in both humans and animals. However, only recently have mutations in potassium channel genes (i.e. KCNQ2 and KCNQ3) been discovered in a human epilepsy, benign familial neonatal convulsions.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide derived from the rat Kv1.1 potassium channel conjugated to KLH

Isotype: IgG

Information d'application

Indications d'application: This antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur KCNA1

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Autre désignation: Kv1.1 Potassium Channel