KCNA1 anticorps

N° du produit ABIN7242236

Détail du produit anti-KCNA1 anticorps

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthetic peptide of human KCNA1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000, IHC 1:15-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KCNA1

Antigène: KCNA1 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 1 (KCNA1))

Autre désignation: KCNA1 (KCNA1 Produits)

Synonymes: anticorps AEMK, anticorps EA1, anticorps HBK1, anticorps HUK1, anticorps KV1.1, anticorps MBK1, anticorps MK1, anticorps RBK1, anticorps KCNA1, anticorps AI840627, anticorps Kca1-1, anticorps Kv1.1, anticorps Mk-1, anticorps Shak, anticorps mceph, anticorps Kcna, anticorps Kcpvd, anticorps potassium voltage-gated channel subfamily A member 1, anticorps potassium voltage-gated channel, shaker-related subfamily, member 1, anticorps fragile site, aphidicolin type, common, fra(12)(q24), anticorps KCNA1, anticorps Kcna1, anticorps FRA12E

Sujet: This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Poids moléculaire: 56 kDa

NCBI Accession: NP_000208

UniProt: Q09470