SPTLC1 anticorps
Aperçu rapide pour SPTLC1 anticorps (ABIN307030)
Antigène
Voir toutes SPTLC1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti Human Serine Palmitoyltransferase 1
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Réactivité croisée
- Humain
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Attributs du produit
- Sphingolipids play essential roles in various cellular events, including proliferation, differentiation, senescence, apoptosis, and inflammatory responses. Serine palmitoyltransferase (SPT) is the initial and rate-limiting enzyme in the de novo sphingolipid biosynthesis, and thus regulates the level of sphingolipids in cells. Immunohistochemical study revealed widespread distribution of the enzyme with most strong expression in brain and digestive tract. Two subunits, SPT1 and SPT2 at a stoichiometry of 1:1, are involved in the enzymatic activity of SPT.
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Purification
- Ammonium Sulfate Precipitation
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Immunogène
- Synthetic peptide derived from the human serine palmitoyltransferase enzyme.
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Isotype
- IgG
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Indications d'application
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
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Autre désignation
- Serine Palmitoyltransferase 1
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Sujet
- Long chain base biosynthesis protein 1, LCB-1, LCB1, Serine-palmitoyl-CoA transferase 1, SPT1, SPT 1, SPT-1
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UniProt
- O15269
Antigène
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