FBXW7 anticorps
Aperçu rapide pour FBXW7 anticorps (ABIN307140)
Antigène
Voir toutes FBXW7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti Human FBXW7
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Réactivité croisée
- Humain
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Attributs du produit
- Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.
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Purification
- Ammonium Sulfate Precipitation
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Immunogène
- Synthetic peptide dervied from the human FBXW7 protein
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Indications d'application
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- FBXW7 (F-Box and WD Repeat Domain Containing 7 (FBXW7))
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Autre désignation
- FBXW7
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Sujet
- F-box and WD-40 domain protein 7, FBXW7, CDC4
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UniProt
- Q969H0
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Pathways
- Signalisation Notch, EGFR Signaling Pathway
Antigène
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