GLI1 anticorps

N° du produit ABIN307152

Détail du produit anti-GLI1 anticorps

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Attributs du produit: Glioma-associated oncogene, Oncogene GLI,Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide derived from human zinc finger protein GLI1.

Information d'application

Indications d'application: Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur GLI1

Antigène: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Autre désignation: Zinc Finger Protein GLI1 (GLI1 Produits)

Synonymes: anticorps GLI, anticorps Gli, anticorps Gli-1, anticorps gli1.1, anticorps AV235269, anticorps Zfp-5, anticorps Zfp5, anticorps GLI family zinc finger 1, anticorps GLI family zinc finger 1 S homeolog, anticorps GLI-Kruppel family member GLI1, anticorps GLI1, anticorps Gli1, anticorps gli1.S, anticorps gli1

Pathways: Signalisation Hedgehog, Dopaminergic Neurogenesis