SMO anticorps
Aperçu rapide pour SMO anticorps (ABIN307155)
Antigène
Voir toutes SMO AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti Human SMO (Smoothened Homolog)
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Réactivité croisée
- Humain
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Attributs du produit
- SMO is a G protein-coupled receptor (GPCR) that putatively associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. The binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). In basal cell carcinoma there are two somatic mutations SMO, D473-> H473 and R562 ->Q562.
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Purification
- Ammonium Sulfate Precipitation
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Immunogène
- Synthetic peptide derived from the human SMO protein
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Isotype
- IgG
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Indications d'application
- Antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- SMO (Smoothened Homolog (Drosophila) (SMO))
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Autre désignation
- SMO (Smoothened Homolog)
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Sujet
- Smoothened homolog [Precursor], SMO, Gx protein, SMO, SMOH
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UniProt
- Q99835
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Pathways
- Signalisation Hedgehog
Antigène
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