P-Selectin anticorps

N° du produit ABIN316863

Cet anticorps anti-P-Selectin Monoclonal Souris (Clone Psel-KO-2-5) (ABIN316863) détecte spécifiquement P-Selectin dans FACS, IP et IHC (p). L’anticorps est réactif avec des échantillons de Humain, Porc et Mouton.

Aperçu rapide pour P-Selectin anticorps (ABIN316863)

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Reactivité: Humain, Porc, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Selectin est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: Psel-KO-2-5

Détail du produit anti-P-Selectin anticorps

Specificité: This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-selectin.

Attributs du produit: Synonyms: SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3, Granule membrane protein 140,Leukocyte-endothelial cell adhesion molecule 3, CD62 antigen-like family member P

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogène: CD62P transfected 300. 19 cells.

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation. Flow Cytometry: Use 10 μL of 1/1-1/50 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur P-Selectin

Antigène: P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))

Autre désignation: CD62P / P-Selectin

Sujet: SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP

ID gène: 6403

UniProt: P16109