Transferrin Receptor anticorps

N° du produit ABIN316908

Cet anticorps anti-Transferrin Receptor est un anticorps Rat Monoclonal détectant Transferrin Receptor dans FACS, IHC (fro) et Func. Adapté pour Souris.

Aperçu rapide pour Transferrin Receptor anticorps (ABIN316908)

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Clone: 8D3

Détail du produit anti-Transferrin Receptor anticorps

Specificité: This antibody recognises CD71, a 95 kDa cell surface protein that is otherwise known as transferrin receptor. This antibody recognises native, soluble and denatured forms of murine CD71. Binding of the 8D3 antibody to CD71 does not inhibit the proliferation of cell lines tested, and does not interfere with the uptake of iron into cells. The antibody has been used as a BBB transporter vector in mice and is suitable for studying CD71 expression, and iron uptake into different tissues, in the Mouse.

Attributs du produit: Synonyms: TfR1, p90, Transferrin receptor protein 1

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

niveau d'endotoxine: < 0.01 Eu/μg

Immunogène: Mouse transformed endothelioma cell line t. end1. Spleen cells from immunised Lewis rats were fused with the cells of the mouse NSOmyeloma cell line

Isotype: IgG2a

Information d'application

Indications d'application: Functional Assays. Flow Cytometry: Use 10 μL of 1/100-1/200 diluetd CD71 antibody to label 10^6 cells. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Commentaires:

Endotoxin Level: <0.01 Eu/μg

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline without preservatives

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: CD71 / TFRC

Sujet: CD71 is a major iron-binding protein, which plays a key role in the transport of iron into cells that require it. In mice, CD71 is widely expressed on a variety of cells, including Sertoli cells and cells which form the blood brain barrier (BBB) in the central nervous system.Synonyms: TfR1, Transferrin receptor protein 1, p90

ID gène: 22042

UniProt: Q62351

Pathways: Transition Metal Ion Homeostasis