PLVAP anticorps (Biotin)

N° du produit ABIN316983

Cet anticorps anti-PLVAP Monoclonal Rat conjugué à Biotin (Clone MECA-32) (ABIN316983) détecte spécifiquement PLVAP dans FACS et IHC (fro). L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour PLVAP anticorps (Biotin) (ABIN316983)

Antigène: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PLVAP est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: MECA-32

Détail du produit anti-PLVAP anticorps (Biotin)

Attributs du produit: Synonyms: Plasmalemma vesicle protein 1, PV1, PV-1, MECA-32 antigen, FELS, Endothelial cell marker,Endothelial cell surface marker, Endothelial Cell Antigen, Plasmalemma vesicle-associatedprotein, Fenestrated endothelial-linked structure protein

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry. Immunohistochemistry on frozen sections: 1/10.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3) and 1 % Bovine Serum Albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PLVAP

Antigène: PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))

Autre désignation: PLVAP

Sujet: PLVAP is a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumour angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.Synonyms: Endothelial Cell Antigen, Endothelial cell marker, Endothelial cell surface marker, FELS, Fenestrated endothelial-linked structure protein, MECA-32 antigen, PV-1, PV1, Plasmalemma vesicle protein 1, Plasmalemma vesicle-associated protein

UniProt: Q9BX97