CD40 anticorps

N° du produit ABIN317137

Cet anticorps Souris Monoclonal détecte spécifiquement CD40 dans WB, IHC (fro) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour CD40 anticorps (ABIN317137)

Antigène: CD40

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: 3B2

Détail du produit anti-CD40 anticorps

Specificité: This antibody specifically recognises CD40.

Attributs du produit: Synonyms: TNFRSF5, CDw40, Bp50, Tumor necrosis factor receptor superfamily member 5, B-cellsurface antigen CD40, CD40L receptor

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogène: CD40-Fc

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on frozen sections: 10.0g/mL. ELISA: 1.0g/mL. Western Blot: 10.0g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Date de péremption: 12 months

Détails sur CD40

Antigène: CD40

Autre désignation: CD40

Sujet: CD40 is a type I transmembrane glycoprotein receptor and member of the TNF-receptor superfamily, primarily expressed by B cells and professional antigen-presenting cells (APCs), which plays a vital role in T cell-B cell interactions and in germinal centre B cell selection. CD40 is a co-stimulatory molecule which mediates its immunoregulatory effects through interaction with its ligand CD154 (CD40L, gp39), playing a role in B cell proliferation and memory development, Ig class switching, activation of APCs and subsequent cytokine production, and the expansion of antigen-specific CD4+ T cells.Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5

ID gène: 958

UniProt: P25942

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints