CD40 anticorps
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- Antigène Voir toutes CD40 Anticorps
- CD40
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD40 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody specifically recognises CD40.
- Attributs du produit
- Synonyms: TNFRSF5, CDw40, Bp50, Tumor necrosis factor receptor superfamily member 5, B-cellsurface antigen CD40, CD40L receptor
- Purification
- Purified IgG prepared by affinity chromatography on Protein A
- Immunogène
- CD40-Fc
- Clone
- 3B2
- Isotype
- IgG1
- Top Product
- Discover our top product CD40 Anticorps primaire
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- Indications d'application
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Immunohistochemistry on frozen sections: 10.0g/mL. ELISA: 1.0g/mL. Western Blot: 10.0g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0mg/mL
- Buffer
- Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3)
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only. - Date de péremption
- 12 months
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- Antigène
- CD40
- Autre désignation
- CD40 (CD40 Produits)
- Synonymes
- anticorps Bp50, anticorps CDW40, anticorps TNFRSF5, anticorps p50, anticorps AI326936, anticorps GP39, anticorps HIGM1, anticorps IGM, anticorps IMD3, anticorps T-BAM, anticorps TRAP, anticorps Tnfrsf5, anticorps TNFSF5, anticorps CD40 molecule, anticorps CD40 antigen, anticorps CD40, anticorps Cd40
- Sujet
- CD40 is a type I transmembrane glycoprotein receptor and member of the TNF-receptor superfamily, primarily expressed by B cells and professional antigen-presenting cells (APCs), which plays a vital role in T cell-B cell interactions and in germinal centre B cell selection. CD40 is a co-stimulatory molecule which mediates its immunoregulatory effects through interaction with its ligand CD154 (CD40L, gp39), playing a role in B cell proliferation and memory development, Ig class switching, activation of APCs and subsequent cytokine production, and the expansion of antigen-specific CD4+ T cells.Synonyms: B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5
- ID gène
- 958
- UniProt
- P25942
- Pathways
- Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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