AKAP13 anticorps

N° du produit ABIN317612

L’anticorps anti-AKAP13 Polyclonal Lapin est utilisé pour la détection de AKAP13 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour AKAP13 anticorps (ABIN317612)

Antigène: AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKAP13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AKAP13 anticorps

Specificité: This antibody detects endogenous levels of AKAP13 Protein.(region surrounding Asp738)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: Western Blot: 1/500-1/1000. ELISA: 1/20000-1/40000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0,05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AKAP13

Antigène: AKAP13 (A Kinase (PRKA) Anchor Protein 13 (AKAP13))

Autre désignation: AKAP13

Sujet: AKAP13 functions as a protein kinase A (PKA)-anchoring protein and acts as an adapter protein to selectively couple G alpha-13 and Rho. It contains a dbl oncogene homology (DH) domain and a pleckstrin homology (PH) domain. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins. AKAP13 augments gene activation by the estrogen receptor and activates estrogen receptor beta by a p38 MAPK-dependent pathway. AKAP13 is involved in the signaling pathways leading to cardiomyocytes hypertrophy.Synonyms: A-kinase anchor protein 13, AKAP-Lbc, BRX, Breast cancer nuclear receptor-binding auxiliary protein, Guanine nucleotide exchange factor Lbc, HT31, Human thyroid-anchoring protein 31, LBC, Lymphoid blast crisis oncogene, Non-oncogenic Rho GTPase-specific GTP exchange factor, P47, Protein kinase A-anchoring protein 13

ID gène: 11214

NCBI Accession: NP_006729

UniProt: Q12802

Pathways: Neurotrophin Signaling Pathway