IL7R anticorps

N° du produit ABIN317658

Cet anticorps anti-IL7R Polyclonal Lapin (ABIN317658) détecte spécifiquement IL7R dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour IL7R anticorps (ABIN317658)

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL7R est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL7R anticorps

Specificité: This antibody detects endogenous levels of IL-7R protein.(region surrounding Gln445)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL7R

Antigène: IL7R (Interleukin 7 Receptor (IL7R))

Autre désignation: CD127 / IL7R

Sujet: The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of an alpha chain and a gamma chain. Both IL7R alpha and IL7R gamma are members of the hematopoietin receptor superfamily. IL7R alpha cDNA encodes a precursor protein containing a signal peptide, an extracellular ligand binding domain, a transmembrane region, and a cytoplasmic region. IL7R alpha transcripts have been observed in spleen, thymus, fetal liver, developing T cells, B cells, mature T cells, and bone marrow derived macrophages.Synonyms: IL-7R-alpha, IL7 receptor alpha, Interleukin-7 receptor subunit alpha

Poids moléculaire: approx. 52 kDa

ID gène: 3575

NCBI Accession: NP_002176

UniProt: P16871

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size