CUX1 anticorps
Aperçu rapide pour CUX1 anticorps (ABIN317667)
Antigène
Voir toutes CUX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of CDP protein.(region surrounding Gln24)
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Purification
- Affinity Chromatography using epitope-specific immunogen.
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Indications d'application
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ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CUX1 (Cut-Like Homeobox 1 (CUX1))
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Autre désignation
- CUTL1 / CDP
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Sujet
- CDP (for CCAAT displacement protein) was identified as a repressor for transcription of developmentally regulated genes. It is a homeodomain protein that appears to compete with transcriptional activating proteins for binding to the promoter regions of various genes. CDP contains three cut repeats which function as DNA binding domains. It has been demonstrated that cut repeat domains have the capacity to bind to DNA in conjunction with or independently of homeodomain DNA binding. CDP has been shown to be the DNA-binding subunit of the HiNF-D complex, which contains cyclin A, Cdc2 and an Rb-related protein in addition to CDP. Histone expression is required for the transition to S phase in the cell cycle. The HiNF-D complex regulates the transcription of Histone H4, H3 and H1 genes, allowing cells to progress from G1 to S phase.Synonyms: CCAAT displacement protein, CUX1, Homeobox protein cut-like 1
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Poids moléculaire
- approx. 164 kDa
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ID gène
- 1523
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NCBI Accession
- NP_001189472
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UniProt
- P39880
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Pathways
- Cellular Glucan Metabolic Process
Antigène
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