Adenosine A2b Receptor anticorps

N° du produit ABIN317695

Cet anticorps Lapin Polyclonal détecte spécifiquement Adenosine A2b Receptor dans WB, IF et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Adenosine A2b Receptor anticorps (ABIN317695)

Antigène: Adenosine A2b Receptor (ADORA2B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adenosine A2b Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-Adenosine A2b Receptor anticorps

Specificité: This antibody detects endogenous levels of Adenosine A2B-R protein.(region surrounding Trp270)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/5000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Adenosine A2b Receptor

Antigène: Adenosine A2b Receptor (ADORA2B)

Autre désignation: Adenosine Receptor A2b

Sujet: Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The adenosine receptors, including adenosine A1-R, adenosine A2A-R, adenosine A2B-R, and adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. The A1-R protein mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via the A2A-R receptor. Collagen synthasis and total protein synthesis are inhibited in certain cells by adenosine, acting via the A2B receptors. Activation of the A3-R receptor inhibits the induction of the cytokine TNFα and blocks the endotoxin CD14 receptor signal transduction pathway.Synonyms: ADORA2B

Poids moléculaire: approx. 34 kDa

ID gène: 136

NCBI Accession: NP_000667

UniProt: P29275

Pathways: cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process