MC1 Receptor anticorps

N° du produit ABIN317707

Cet anticorps Lapin Polyclonal détecte spécifiquement MC1 Receptor dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MC1 Receptor anticorps (ABIN317707)

Antigène: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MC1 Receptor est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-MC1 Receptor anticorps

Specificité: This antibody detects endogenous levels of MC1-R protein (region surrounding Val312).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MC1 Receptor

Antigène: MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))

Autre désignation: MC1-R

Sujet: The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.Synonyms: MC1R, MSH-R, MSHR, Melanocortin receptor 1, Melanocyte-stimulating hormone receptor, Melanotropin receptor

Poids moléculaire: approx. 35 kDa

ID gène: 4157

NCBI Accession: NP_002377

UniProt: Q01726

Pathways: cAMP Metabolic Process, Feeding Behaviour