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BAI1 anticorps

BAI1 Reactivité: Humain, Souris WB, IHC (p), IF, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN317742
  • Antigène Voir toutes BAI1 Anticorps
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Reactivité
    • 41
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 40
    • 1
    Lapin
    Clonalité
    • 40
    • 1
    Polyclonal
    Conjugué
    • 21
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BAI1 est non-conjugé
    Application
    • 18
    • 15
    • 13
    • 13
    • 12
    • 12
    • 7
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificité
    This antibody detects endogenous levels of BAI-1 protein.(region surrounding Gln732)
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product BAI1 Anticorps primaire
  • Indications d'application
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2 with 0.05 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
    Autre désignation
    BAI1 (BAI1 Produits)
    Synonymes
    anticorps BAI1, anticorps GDAIF, anticorps B830018M07Rik, anticorps R75078, anticorps mKIAA4089, anticorps brain-specific angiogenesis inhibitor 1, anticorps adhesion G protein-coupled receptor B1, anticorps BAI1, anticorps ADGRB1, anticorps LOC100228084, anticorps Adgrb1
    Sujet
    Brain-specific angiogenesis inhibitors, including BAI-1, BAI-2 and BAI-3, are integral membrane proteins belonging to the G protein-coupled receptor 2 family. In addition to inhibiting angiogenesis in the brain, BAI proteins are also expressed in the heart, thymus, skeletal muscle, and a variety of cell lines. BAI-1 protein is specifically expressed in the brain and found to localize to the cytoplasm and membrane in neuronal cells of the cerebral cortex. Reduced expression of BAI-1 in some glioblastoma cell lines and cancer tissues implicates the functional role of BAI-1 as an inhibitor of angiogenesis. The exact mechanisms underlying BAI-1 anti-angiogenetic activity are still being investigated. BAI-1 may be involved in mediating the p53 signal in suppression of glioblastoma, as well as in cell adhesion and signal transduction. Additional research shows an inverse correlation with vascularization and BAI-1 expression in both colorectal carcinomas and pulmonary adenocarcinomas.Synonyms: BAI-1, Brain-specific angiogenesis inhibitor 1
    Poids moléculaire
    approx. 174 kDa
    ID gène
    575
    NCBI Accession
    NP_001693
    UniProt
    O14514
    Pathways
    Signalisation p53
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