CA5B anticorps
Aperçu rapide pour CA5B anticorps (ABIN317824)
Antigène
Voir toutes CA5B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody detects endogenous levels of CA VB protein.(region surrounding asn280)
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Purification
- Affinity Chromatography using epitope-specific immunogen
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Indications d'application
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CA5B (Carbonic Anhydrase VB, Mitochondrial (CA5B))
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Autre désignation
- Carbonic Anhydrase 5B
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Sujet
- Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide.CAs show extensive diversity in their distribution and subcellular localization.They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VB, also known as carbonate dehydratase VB, is one of two isoforms of CA V. It localizes to the mitochondria and is involved in metabolic processes. CA VB is predominantly expressed in heart, pancreas, lung, placenta, kidney and skeletal muscle. It exhibits highest homology with family member CA VA (the second isoform of CA V), however, unlike CA VA, it is not expressed in the liver, suggesting that it plays a significantly different physiological role.Synonyms: CA-VB, CA5B, Carbonate dehydratase VB, Carbonic anhydrase VB
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Poids moléculaire
- approx. 38 kDa
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ID gène
- 11238
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NCBI Accession
- NP_009151
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UniProt
- Q9Y2D0
Antigène
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