DNAJB11 anticorps

N° du produit ABIN317830

Détail du produit anti-DNAJB11 anticorps

Antigène: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: ERdj3 antibody detects endogenous levels of ERdj3 protein.(region surrounding Lys66)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DNAJB11

Antigène: DNAJB11 (DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11))

Autre désignation: DNAJB11 (DNAJB11 Produits)

Synonymes: anticorps MGC75796, anticorps MGC81924, anticorps ABBP-2, anticorps ABBP2, anticorps DJ9, anticorps Dj-9, anticorps EDJ, anticorps ERdj3, anticorps ERj3, anticorps ERj3p, anticorps PRO1080, anticorps UNQ537, anticorps hDj-9, anticorps 1810031F23Rik, anticorps AL024055, anticorps Dj9, anticorps LRRGT00084, anticorps cb954, anticorps DnaJ heat shock protein family (Hsp40) member B11, anticorps DnaJ heat shock protein family (Hsp40) member B11 S homeolog, anticorps DnaJ (Hsp40) homolog, subfamily B, member 11, anticorps dnajb11, anticorps DNAJB11, anticorps dnajb11.S, anticorps Dnajb11

Sujet: Members of the heat shock protein 40 (HSP 40) family of proteins all contain a highly conserved J domain that associates with HSP 70 and regulates the function of HSP 70 by activating its adenosine triphosphatase activity. ERdj3, an HSP 40 chaperone, is expressed in the ER lumen, where it interacts with BiP, a molecule involved in retrotranslocating proteins out of the ER. ERdj3 also associates with several other protein substrates, including unfolded light chains, a nonsecreted Ig light chain mutant and a VSV-G ts045 mutant. Shiga toxin (Stx) is a bacterial tool that enzymatically inactivates the 28S rRNA, inhibiting protein synthesis of infected cells. Stx also interacts with ERdj3 and Sec 61 to form a complex through which proteins are retrotranslocated to the cytoplasm. ERdj3 may play a role in the ER quality control system.Synonyms: APOBEC1-binding protein 2, DnaJ homolog subfamily B member 11, EDJ, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, ER-associated dnaJ protein 3, ERJ3, ERdj3, ERj3p, HEDJ, PSEC0121, PWP1-interacting protein 4, hDj9

Poids moléculaire: approx. 40 kDa

ID gène: 51726

NCBI Accession: NP_057390

UniProt: Q9UBS4

Pathways: ER-Nucleus Signaling