ADRB3 anticorps

N° du produit ABIN317855

L’anticorps anti-ADRB3 Polyclonal Lapin est utilisé pour la détection de ADRB3 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour ADRB3 anticorps (ABIN317855)

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADRB3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ADRB3 anticorps

Specificité: AR-β3 antibody detects endogenous levels of AR-β3 protein.(region surrounding Leu291)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ADRB3

Antigène: ADRB3 (Adrenergic, beta-3-, Receptor (ADRB3))

Autre désignation: beta-3 Adrenergic Receptor

Sujet: The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. β-adrenergic bound to adrenaline activates adenylyl cyclase, while α2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the α2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories and they are designated 5-HT1, 5-HT2, 5-HT3, 5-HT4, 5-HT5, 5-HT6 and 5-HT7. The 5-HT1 receptors have further been subdivided into 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D, 5-HT1E and 5-HT1F receptors.Synonyms: ADRB3, ADRB3R, B3AR, Beta-3 adrenoceptor

Poids moléculaire: approx. 36 kDa

ID gène: 155

NCBI Accession: NP_000016

UniProt: P13945

Pathways: cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Brown Fat Cell Differentiation