DRD4 anticorps

N° du produit ABIN317857

Détail du produit anti-DRD4 anticorps

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: D4DR antibody detects endogenous levels of D4DR protein.(region surrounding Leu396)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 15 mM Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DRD4

Antigène: DRD4 (Dopamine Receptor D4 (DRD4))

Autre désignation: Dopamine D4 Receptor (DRD4 Produits)

Synonymes: anticorps Drd4b, anticorps si:ch211-69h5.1, anticorps zgc:123021, anticorps D4DR, anticorps AW125663, anticorps D4R, anticorps Drd-4, anticorps D4RA, anticorps DRD4, anticorps Drd4c, anticorps dopamine receptor D4 related sequence, anticorps dopamine receptor D4, anticorps dopamine receptor D4b, anticorps drd4-rs, anticorps DRD4, anticorps Drd4, anticorps SRU_2808, anticorps MSMEG_3522, anticorps drd4b

Sujet: This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats, the sequence shown contains four repeats.DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens.Synonyms: D(2C) dopamine receptor, D(4) dopamine receptor, DRD4

Poids moléculaire: approx. 50 kDa

ID gène: 1815

NCBI Accession: NP_000788

UniProt: P21917

Pathways: cAMP Metabolic Process, Synaptic Membrane, Proton Transport, Photoperiodism, Negative Regulation of Transporter Activity