VIPR1 anticorps

N° du produit ABIN317871

Détail du produit anti-VIPR1 anticorps

Antigène: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VIPR1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of VPAC1 protein. (region surrounding Val371)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur VIPR1

Antigène: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Abstract: VIPR1 Produits

Synonymes: anticorps HVR1, anticorps II, anticorps PACAP-R-2, anticorps PACAP-R2, anticorps RDC1, anticorps V1RG, anticorps VAPC1, anticorps VIP-R-1, anticorps VIPR, anticorps VIRG, anticorps VPAC1, anticorps VPAC1R, anticorps VPCAP1R, anticorps CVIPR, anticorps AV071699, anticorps VIP-R1, anticorps RATVASREC, anticorps VASREC, anticorps VIPR1, anticorps LOC100226500, anticorps vipr1, anticorps hvr1, anticorps rdc1, anticorps v1rg, anticorps vipr, anticorps virg, anticorps vapc1, anticorps vpac1, anticorps vpcap1, anticorps vpac1-r, anticorps VIP-R, anticorps vasoactive intestinal peptide receptor 1, anticorps vasoactive intestinal peptide receptor 1b, anticorps vasoactive intestinal peptide receptor 1 S homeolog, anticorps vasoactive intestinal polypeptide receptor, anticorps VIPR1, anticorps Vipr1, anticorps vipr1b, anticorps vipr1, anticorps vipr1.S, anticorps LOC100303683

Sujet: The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.Synonyms: PACAP-R-2, PACAPR2, Pituitary adenylate cyclase-activating polypeptide type II receptor, VIP-R1, VIPR-1, VIPR1, Vasoactive intestinal polypeptide receptor 1

Poids moléculaire: approx. 52 kDa

ID gène: 7433

NCBI Accession: NP_004615

UniProt: P32241