GNGT1 anticorps

N° du produit ABIN317913

Cet anticorps anti-GNGT1 Polyclonal Lapin (ABIN317913) détecte spécifiquement GNGT1 dans WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour GNGT1 anticorps (ABIN317913)

Antigène: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GNGT1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GNGT1 anticorps

Specificité: Gα t1 antibody detects endogenous levels of Gα t1 protein.(region surrounding Met104)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GNGT1

Antigène: GNGT1 (G Protein gamma Transducing Activity Polypeptide 1 (GNGT1))

Autre désignation: G Protein gamma T1

Sujet: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (i.e. adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein α, β and γ polypeptides are encoded by at least 16, 4 and 7 genes, respectively. Most interest in G proteins has been focused on their α subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. Four distinct classes of Gα subunits have been identified, these include Gs, Gi, Gq and Gα 12/13. The Gi class comprises all the known α subunits that are susceptible to pertussis toxin modifications, including Gα i-1, Gα i-2, Gα i-3, Gα o, Gα t1, Gα t2, Gα z and Gα gust. In the well characterized visual system, photorhodopsin catalyzes the exchange of guanine nucleotides bound to the visual transducin Gα subunits (Gα t1 in rod cells and Gα t2 in cone cells).Synonyms: GNGT1, Guanine nucleotide-binding protein G T subunit gamma-T1, Transducin gamma chain

Poids moléculaire: approx. 36 kDa

ID gène: 2792

NCBI Accession: NP_068774

UniProt: P63211

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction