Nerve Growth Factor anticorps

N° du produit ABIN318395

L’anticorps Lapin Polyclonal anti-Nerve Growth Factor a été validé pour WB, Func et EIA. Il convient pour détecter Nerve Growth Factor dans des échantillons de Humain et Souris.

Aperçu rapide pour Nerve Growth Factor anticorps (ABIN318395)

Antigène: Nerve Growth Factor (NGF)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nerve Growth Factor est non-conjugé

Application: Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Détail du produit anti-Nerve Growth Factor anticorps

Specificité: This antibody recognizes both the 2.5S and 7S forms of Mouse NGF beta, a secreted peptide involved in the development and maintenance of the sympathetic and sensory nervous systems. In a standard bioassay, this antibody neutralises the activity of 3.0 ng/mL NGF 2.5S when used at a concentration of around 0.5 μg/mL.

Purification: Affinitv Chromatography

Immunogène: Affinity purified Mouse 2.5S NGF

Isotype: IgG

Information d'application

Indications d'application: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1.0 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09 % Sodium Azide is recommended. For Functional Studies do not Add Sodium Azide.

Concentration: 1.0 mg/mL

Buffer: PBS, None, None

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20 °C.

Détails sur Nerve Growth Factor

Antigène: Nerve Growth Factor (NGF)

Autre désignation: NGF

Sujet: Nerve growth factor (NGF) is one of a family of neurotrophins that induce the survival and proliferation of neurons. In cell culture, NGF induces the formation of neurite projections and, in vivo, may stimulate the innervation of tissues. NGF plays a role in the repair, regeneration, and protection of neurons, and as such could serve as a therapeutic agent in neurodegenerative conditions such as Alzheimer's disease. NGF enhances survival, growth, neurotransmitter biosynthesis of sympathetic and sensory neurons, neurotrophic factor, cutaneous innervation, growth, differentiation and survival of B lymphocytes. It also has a possible role in allergy and tissue repair. NGF is found in the hypothalamus, pituitary, thyroid gland, testes, epididymis, vascular smooth muscle cells, fibroblasts, mast cells and eosinophils. NGF is upregulated by glutamate, vitamin D3, IL6, FGF basic, astrocyte specific IL1, TNF alpha, PDGF and TGF beta. It is downregulated by GABAergic neuronal activity, glucocorticoids and Schwann cell-specific TGF beta.Synonyms: Beta-NGF, Beta-nerve growth factor, NGFB

ID gène: 4803

NCBI Accession: NP_002497

UniProt: P01138

Pathways: Regulation of Cell Size