Cadherin 13 anticorps (N-Term)

N° du produit ABIN318711

Cet anticorps anti-Cadherin 13 Polyclonal Lapin (ABIN318711) détecte spécifiquement Cadherin 13 dans WB et IF. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Cadherin 13 anticorps (N-Term) (ABIN318711)

Antigène: Cadherin 13 (CDH13)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cadherin 13 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Cadherin 13 anticorps

Épitope: N-Term

Specificité: This antibody recognises T-Cadherin.

Purification: Affinity Chromatography.

Immunogène: Synthetic peptide corresponding to N-terminus of human Cadherin-13.

Isotype: IgG

Information d'application

Indications d'application: Western Blot (0.5-1.0 μg/mL): This antibody detects a band/s of approximately 78 kDa in3T3 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid multiple freeze/thaw cycles.

Détails sur Cadherin 13

Antigène: Cadherin 13 (CDH13)

Autre désignation: Cadherin-13

Sujet: T-cadherin is a 78 kDa, calcium-dependent, glycoprotein. While T-cadherin is a member of the cadherin family, it lacks their conserved cytoplasmic region, being instead anchored to the plasma membrane via glycosylphosphatidylinositol linkage. It is expressed in the heart and CNS with the exception of the cerebellum and spinal cord. Cadherin 13 is classified as a cell-cell adhesion molecule, although it is likely that it's role is in signalling and not physical adhesion. It is involved in regulating low-density lipoprotein-initiated cell proliferation, keratinocyte proliferation, neural cell growth and may play a role in metabolic regulation. Cadherin 13 protects endothelial cells from oxidative stress-induced apoptosis and may contribute to progression of vascular disorders such as atherosclerosis, restenosis and tumour angiogenesis.Synonyms: CDH13, CDHH, Cadherin H, Cadherin T, H-Cadherin, Heart cadherin, P105, T-Cadherin, Truncated cadherin

ID gène: 1012

NCBI Accession: NP_001248

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization