Carabin anticorps (N-Term)

N° du produit ABIN318913

Cet anticorps Lapin Polyclonal détecte spécifiquement Carabin dans WB et IHC (p). Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour Carabin anticorps (N-Term) (ABIN318913)

Antigène: Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Carabin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Carabin anticorps

Épitope: N-Term

Specificité: This antibody recognises Carabin, also known as TBC1 domain family member 10C (TBC1D10C), a 50 kDa protein belonging to the TBC1 domain family of proteins. This antibody does not cross react with either TBC1D10A or TBC1D10B.

Purification: Purified

Immunogène: A 17 amino acid peptide from near the amino terminus of human Carabin.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 2g/mL, detects a band of approximately 55 kDa in human spleen tissuecell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide (NaN3)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for up to one month or (in aliquots) at -20 °C for longer.

Détails sur Carabin

Antigène: Carabin (TBC1D10C) (TBC1 Domain Family, Member 10C (TBC1D10C))

Autre désignation: Carabin

Sujet: Carabin differs from other members of the TBC1 domain protein family, which appear to play a role in the regulation of cell growth and differentiation. Studies demonstrate that Carabin is part of a negative regulatory loop for the intracellular TCR signalling pathway and acts as an inhibitor of the Ras signalling pathway. Carabin is also believed to mediate crosstalk between calcineurin and Ras. Carabin is most abundantly expressed in spleen and peripheral blood leucocytes.Synonyms: TBC1 domain family member 10C, TBC1D10C

ID gène: 374403

NCBI Accession: NP_940919

UniProt: Q8IV04