CCR8 anticorps (AA 183-201)
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- Antigène Voir toutes CCR8 Anticorps
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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Épitope
- AA 183-201
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CCR8 est non-conjugé
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Application
- Western Blotting (WB)
- Specificité
- This antibody recognises the chemokine receptor CCR8, also known as CDw198, which has been identified as a co-receptor for HIV infection. CCR8 is a receptor for the human chemokine 1-309 which is expressed on spleen, thymus and T lymphoblastic cell lines. This antibody detects a band of approximately 50 kDa.
- Purification
- Purified
- Immunogène
- Peptide corresponding to amino acids 183 to 201 of human CDw198 (CCR8).
- Isotype
- IgG
- Top Product
- Discover our top product CCR8 Anticorps primaire
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- Indications d'application
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Western Blot: 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate buffered saline containing 0.02 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
- Autre désignation
- CDw198 / CCR8 (CCR8 Produits)
- Synonymes
- anticorps CC-CKR-8, anticorps CCR-8, anticorps CDw198, anticorps CKRL1, anticorps CMKBR8, anticorps CMKBRL2, anticorps CY6, anticorps GPRCY6, anticorps TER1, anticorps C-C, anticorps C-C CKR-8, anticorps CKR-8, anticorps Cmkbr8, anticorps mCCR8, anticorps C-C motif chemokine receptor 8, anticorps chemokine (C-C motif) receptor 8, anticorps CCR8, anticorps Ccr8
- Sujet
- CCR8 is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation regulated cytokine (TARC) and macrophage inflammatory protein 1 beta (MIP1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. CCR8 expression has been reported in spleen and thymus, natural killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. CCR8 is also believed to be alternative coreceptor with CD4 for HIV-1 infection.Synonyms: C-C CKR-8, C-C chemokine receptor type 8, CC-CKR-8, CC-chemokine receptor CHEMR1, CCR-8, CKRL1, CMKBR8, CMKBRL2, Chemokine receptor-like 1, GPR-CY6, TER1
- ID gène
- 1237
- NCBI Accession
- NP_005192
- UniProt
- P51685
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